i don't know how complicated one design option is versus another, but if a design option isn't too complicated, i tend to use custom created Renovation filters where anything to do with, say, Option 1, is pinned to the Option 1 Renovation Filter:
Option 2 will have it's own Reno filter & anything to do with OPT2 will be pinned to the OPT2 reno filter, etc...
you may still have to create specific layers & layer combinations between the options, but you might not need that many files to set up. perhaps just the separate file to isolate the Design Options modelling & documentation away from the main model (if you need to).
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