I have been running AC22 (UKI) build 4023 on Mojave 10.14.1 for weeks with only minor issues e.g really slow AC startup. This morning I was auto updated 10.14.2 and AC fired up ok.
Silly thing but have you tried completely shutting down and restarting? It sometimes takes a shut down to properly finish an update.
As well as which version of AC you are running, how old is your iMac? Mine is a late 2013 model.
Apple iMac Intel i9 / macOS Sonoma / AC27UKI (most recent builds.. if they work)