Is the drawing frame still there, or does it vanish completely? Turn on drawing frames in the On Screen View Options to help you.
A few things you could check -
Is the drawing on a layer which gets turned off perhaps? You can double-check what drawings are placed already by looking in the layout book in the navigator, and see what is listed.
Have you moved the section/elevation marker on plan so it is no longer 'looking' at the building any more?
Have you accidently assigned a layer combination where all elements are turned off?
You also don't say which version of AC you are using, on what type of hardware. Put this information on your signature permanently, as it is useful for diagnosing problems.
If the drawing you place is set to FIT FRAME TO DRAWING then it may not be on the layout sheet, but somewhere off the page. Try a FIT IN WINDOW to check.
Erika
Architect, Consultant
MacBook Pro Retina, 15-inch Yosemite 2.8 GHz Intel Core i7 16 GB 1600 MHz DDR3
Mac OSX 10.11.1
AC5-18
Onuma System
"Implementing Successful Building Information Modeling"
I found out the problem should be caused by the outdated hotfix.
Now, after installation of the latest hotfix, updating the drawing which placed onto layout after the latest hotfix would not be disappear anymore !!! I am happy man now.