I have had to face the similar scenario just recently. This is what has actually worked best for us:
1. create a master layout with a black fill on it.
2. define a special pen set that will have reverse pen colours (eg. all blacks to whites and grey ones like let's say pen colour R10G10B10 will become R245(255-10)G245(255-10)B245(255-10) etc..) apply it on all layout drawings.
We have created two sets of layouts with white and black masters, then copied drawings from one to another and changed just the pen set of those drawings.
AFAIK there is no automatic inverse print feature in AC. Remember if you change the background to black it will not help you because the background colour is ignored when you print.
::rk