I assume you mean you publish your layouts to DWG?
You can set up folders in publisher which contain several layouts (or just use the folders from your layout book, assuming you are using those) if you select one of these folders in Publisher, you can tick 'Merge to one DWG file' at the bottom. This will put all the layouts in that folder into the one file.
Erwin Edel, Project Lead, Leloup Architecten
www.leloup.nlArchiCAD 9-26NED FULL
Windows 10 Pro
Adobe Design Premium CS5